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Search Results for " gamma-aminobutyric acid receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T4440 Saclofen GABA Receptor
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function...
TQ0023 Lorediplon GABA Receptor
Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.
T5754 Kavain NF-κB , GABA Receptor
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.
T14571 Bifenazate GABA Receptor
Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.
TQ0119 Cirsimaritin GABA Receptor
Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.
TN1023 Miltirone P450 , GABA Receptor
Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.
T15775 Lotilaner GABA Receptor , Parasite
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
T10618 Broflanilide GABA Receptor
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR (IC50: 1.3 nM).
T7794 Zuranolone GABA Receptor
Zuranolone is an agonist of GABAA receptor.
T7557 Guvacine hydrochloride GABA Receptor
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
T3782 Jujuboside A transporter , GABA Receptor
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, having neurophysiological inhibitory effects, used as a potential therapeutic agent for the treatment of Alzheimer s disease.
T0508 γ-Aminobutyric acid Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid GABA Receptor , Endogenous Metabolite
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.
T8036 6-Methylflavone GABA Receptor
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
T16539 Piperazine citrate GABA Receptor
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic.
T5375 Loreclezole GABA Receptor
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
T26600 Alpidem Ananxyl GABA Receptor
Alpidem (Ananxyl) is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. Alpidem has nanomolar bin...
T2990 Phenibut Phenybut,Fenigam,Fenibut,PhGABA,Aminophenylbutyric acid,β-Phenyl-γ-aminobutyric acid GABA Receptor
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).
T3644 U93631 GABA Receptor
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude...
T11822 LAU159 GABA Receptor
LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).
T7136 AZD-6280 GABA Receptor
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
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TargetMol